Pinnick Oxidation

Gentle Oxidation method for Aldehyde to Carboxylic Acid.

The Pinnick Oxidation is an economical and gentle method to oxidize aldehydes to carboxylic acids.¹

Summary

The reaction entry summary. Find the general scheme and full summarized mechanisms here.

General Mechanism

This section briefly summarizes steps to find the product and perform the mechanisms.

Quick steps to finding the product

1. Identify the reagents.
2. Identify the product which needs to be formed.
3. Form the HO-Cl reagent needed to form the Carboxylic Acid.
4. React the Aldehyde with HO-Cl and form the Carboxylic Acid product.
5. Scavenge the HO-Cl by-product.

Full Aldehyde to Carboxylic Acid

Always remember to repeatedly practice your mechanisms and getting your reagents correct. Take advantage of our materials and/or keep practicing on a whiteboard or paper until you get it right every single time.

References

1. Lindgren, B. O.; Nilsson, T.; Husebye, S.; Mikalsen, Ø.; Leander, K.; Swahn, C.-G. Preparation of Carboxylic Acids from Aldehydes (Including Hydroxylated Benzaldehydes) by Oxidation with Chlorite. Acta Chem. Scand. 1973, 27, 888–890. DOI: 10.3891/acta.chem.scand.27-0888